The Antibacterial Effect of Humulus lupulus (Hops) against Mycobacterium bovis BCG: A Promising Alternative in the Fight against Bovine Tuberculosis?

The female flowers of the Humulus lupulus plant or Hops have been used extensively within brewing industry for their aroma and bitterness properties. It was also found that beer contained hops less likely to spoil, thus revealing antimicrobial potential these plants. One species bacteria, Mycobacterium spp., is particular interest as it causative agent both human animal forms tuberculosis (TB). In this study an aqueous extraction process employed analyse antibacterial properties 50 hop extracts (45 individual variants); against M. bovis BCG. Using agar well diffusion assay we all exhibited a level inhibitory activity which ranged from 1.2 mm (+/? 0.08 mm) in case variant; Target, 15.7 0.45 variant Citra. Citra had minimum concentration (MIC) bactericidal (MBC) 16% v/v. This first wide range BCG recommends further research focuses on other Mycobacteria synergy effect components.